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洛伐他汀对慢性心力衰竭的治疗效应 被引量:2

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摘要 目的:常规抗心衰治疗的基础上加用洛伐他汀治疗慢性心力衰竭,以观察其对慢性心力衰竭的治疗效应。方法:选取慢性心力衰竭患者66例随机分为两组,对照组32例,给予常规强心、利尿等抗心衰治疗;治疗组34例,除常规强心、利尿等抗心衰治疗外加用洛伐他汀片20mg每晚一次顿服,各治疗6个月。观察治疗前后两组患者的心脏超声指标及临床症状的变化。结果:两组患者较治疗前左室舒张末内径(LVED)与左室收缩末内径(LVES)均缩小,左室射血分数(LVEF)提高,且治疗组较对照组改变更明显,具有统计学差异(P<0.05);两组临床症状及NYHA分级较治疗前均有所改善,但两组临床心功能改善的有效率尚无明显的统计学差异(P>0.05)。结论:在常规抗心力衰竭药物治疗基础上加用洛伐他汀,可进一步改善慢性心力衰竭患者的心功能。
作者 史志农
出处 《牡丹江医学院学报》 2010年第3期50-51,共2页 Journal of Mudanjiang Medical University
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参考文献5

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