头孢美唑钠预防剖宫产围手术期感染的临床研究

Clinical study on cefmetazole sodium for prophylaxis on infection in perioper active period of cesarean section

目的探讨择期剖宫产术抗生素应用的理想时机和方法。方法 100例择期行剖宫产的病人被随机分为实验组(n=50)和对照组(n=50),进行前瞻性随机对照试验,观察两组临床效果和经济学效果,并作统计学对比分析。结果两组患者术后最高体温,腹壁切口愈合,白细胞计数情况、住院天数比较无统计学差异(P>0.05)。人均抗生素用量、人均抗生素费用比较有显著性差异(P<0.01)。结论择期剖宫产围手术期预防性抗生素应用,能有效预防术后感染,是一种既有效又经济的理想方案。

Objective To explore the optimization method of antibiotics for elective cesarean section.Methods 100 cases of elective cesarean section patients were randomly divided into two groups（n=50/group）,the study group with antibiotics in perioperative period and the control group with antibiotics after operation.The clinical and economic effects were investigated and analyzed.Results The highest temperature,white blood cell count,wound healing and the days of hospitalization were no significant differences（P〉0.05）.The amount of antibioctics and medical payments were significant differences（P〈0.01）.Conclusion The antibiotics in perioperative period was effective method for preventing infection in elective cesarean section patients.