青春期多囊卵巢综合征研究进展被引量：1

A Progress in Adolescents with Polycystic Ovary Syndrome

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摘要青春期多囊卵巢综合征(PCOS)发病率高,病因不明,临床表现和生化特征复杂多样,不易与正常青春期表现进行区分,故临床医生应该重视青春期PCOS的早期诊断和及时治疗。本文就青春期PCOS的病因,发病机制,临床表现,诊治等方面的最新进展作一综述。 Polycystic ovarian syndrome （PCOS） has high incidence, unclear etiology and complex clinical manifestation and biochemical features, which is uneasy to be distinguished from normal adolescent appearance, so clinicians should pay attention to early diagnosis and timely treatment of adolescent PCOS. This article reviewed new progress of etiology, pathogenesis, clinical manifestations, diagnosis and treatment of adolescent PCOS.

作者吴绮霞甄小文余芳冯满欢邝绮慈

机构地区广东省开平市中心医院妇产科

出处《临床医学工程》 2010年第7期156-158,共3页 Clinical Medicine & Engineering

关键词多囊卵巢综合征青春期雄激素过多 Polycystic ovarian syndrome Adolescence Hyperandrogenism

分类号 R711.75 [医药卫生—妇产科学]

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参考文献14

1Chang RJ, Coffier MS. Polycysti ovary syndrome[J]. Early detection in the adolesccnt[J]. Clin Obstet Gynecol, 2007, 50 (1): 178-187.
2Franks S. Polycystic ovary syndrome in adolescents [J]. International Journal of Obesity, 2008, 32 (1): 1035-1041.
3李梅,刘嘉茵,崔毓桂.青春期多囊卵巢综合征及其代谢特征[J].国际生殖健康／计划生育杂志,2008,27(1):42-44. 被引量：12
4Franks S. Candidate genes in women with polycystic ovary syndrome [J]. Fertil Steril, 2006, 86(Suppl 1): S15.
5Powell BL, Haddad L, Bennett A, et al. Analysis of multiple data sets reveals no association between the insulin gene variable number tandem repeat element and polycystic ovary syndrome or related traits[J]. J Clin Endocrinol Metab, 2005, 90: 2988.
6Diamanti-Kandarakis E, Alexandraki K, Bergiete A, et al. Presence of metabolic risk factors in nonobese PCOS sisters: evidence ofheritability of insulin resistance[J]. J Endocrinol Invest, 2004, 27:931.
7Kriplani A, Agarwal N. Effects of metformin on clinical and biochemical parameters in polycystic ovary syndrome [J]. Reprod Med, 2004, 49 (5) : 361-367.
8李琳.PCOS与青春期胰岛素抵抗[J].实用妇产科杂志,2005,21(9):522-524. 被引量：12
9郁琦.多囊卵巢综合征诊治标准专家共识[J].中国实用妇科与产科杂志,2007,23(6):474-474. 被引量：107
10Dunaif A, SeoR D, Finegood D, et al. The insulin-sensitizing agent troglitazone improves metabolic ovar syndrome [J].J Clin Endocrinol Metab, 1996, 81: 3299.

二级参考文献37

1[1]Michael J, Slowey MD,Concord NC.Polycystic ovary syndrome :New perspective on old problem . Southern Medical Journal , 2001, 94(2):190-196.
2[2]Ajossa S, Guerriero S, Paolelti AM, et al .The antiandrogenic effect of flutamide improves uterine perfusion in women with polycystic ovary syndrome. Fertil Steril, 2002,77(6): 1136-1140.
3[3]George Mastorakos G, Koliopoulos C, Creatsas G. Androgen and lipid profiles in adolescents with polycystic ovary syndrome who were treated with two forms of combined oral contraceptives. Fertil Steril, 2002,77(5):919-927.
4[4]Telli MH , Yildirim M, Noyan V, et al. Serum leptin levels in patients with polycystic ovary syndrome. Fertil Steril, 2002, 77(5): 932-935.
5[5]Diamanti-Kandarakis E, Spina G, Kouli C, et al. Imcreased endothelin -I levels in women with polycystic ovary syndrome and the beneficial effect of meformin therapy. J Clin Endocrinol Metab ,2001, 86(10):4666-4673.
6[6]Vandermolen DT, Ratts VS, Evans WS, et al .Metformin increases the ovulatory rate and pregnancy rate with clomiphene citrate in patients with polycystic ovary syndrome who are resistant to clomiphene citrate alone. Fertil Steril , 2001,75(3):310-315.
7[7]Ng EH, Wat NM, Ho PC. Effects of metformin on ovulation rate, hormonal and metabolic profiles in women with clomiphene resistant polycystic ovaries: a randomized,double-blinded placebo-controlled trial. Hum Reprod, 2001,16(8): 1625-1631.
8[8]De Leo V, La Maca A, Ditto A, et al. Effects of metformin on gonadotropin -induced ovulation women with polysystic ovary syndrome. Fertil Steril, 1999, 72(2):282-285.
9[9]Jakubowicz DJ, Iuorno MJ, Jakubowicz S, et al. Effects of metformin on early pregnancy loss in the polycystic ovary syndrome. J Clin Endocrinol Metab. 2002,87(2): 524-529.
10[10]Glueck CJ, Wang P, Kobayashi S, et al. Metformin therapy throughout pregnancy reduces the development of gestational diabetes in women with polycystic ovary syndrome. Fertil Steril, 2002,77(3): 520-525.