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叶酸-聚酰胺-胺聚合物靶向给药系统的研究进展 被引量：2

Progress of Folate-PAMAM Dendrimer Conjugates as Drug Carriers in Targeted Drug Delivery System
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摘要 简要介绍了聚酰胺-胺树状大分子(PAMAM-D)的特点,叶酸修饰的PAMAM-D复合物的主动靶向性机制,及其在抗肿瘤、基因治疗等领域的研究进展。 The characteristics of polyamidoamine dendrimer（PAMAM-D） and the active targeting mechanism of folic acid modified PAMAM-D conjugates are briefly introduced.The progress of the application of the conjugates is reviewed in the fields of anti-tumor,gene therapy,etc.
作者 孙武 朱宏
机构地区 南京工业大学材料科学与工程学院
出处 《中国医药工业杂志》 CAS CSCD 北大核心 2010年第7期538-542,共5页 Chinese Journal of Pharmaceuticals
关键词 聚酰胺-胺树状大分子 叶酸修饰 靶向药物输送 综述 polyamidoamine dendrimer folic acid modified targeted drug delivery system review
分类号 R944.9 [医药卫生—药剂学]
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参考文献21

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共引文献24

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中国医药工业杂志
2010年 第7期

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