间苯三酚和米索前列醇对宫腔镜手术前宫颈扩张效果的比较

Comparison of Phloroglucinol and Misoprostol on Cervical Dilation Effect before Hysteroscopic Operation

目的对比间苯三酚和米索前列醇对宫腔镜手术前患者宫颈扩张的效果。方法将96例宫腔镜电切术病人随机分成两组:I组47例,术前30 min肌肉注射间苯三酚80 mg;II组49例,为对照组,术前晚阴道用米索前列醇0.4 mg。观察宫颈扩张情况、术者对手术操作的满意率、手术时间和术中出血量。结果Ⅰ组病人89.36%可无阻力通过9号Hegar氏扩张棒,术者操作的满意率为89.39%,Ⅱ组81.63%的病人可无阻力通过9号Hegar氏扩张棒,术者操作的满意率为71.43%,术者操作满意率Ⅰ、Ⅱ组相比差异有统计学意义(P<0.01)。I组无1例并发症发生,术中血量较II组少,差异有统计学意义。结论间苯三酚80 mg术前肌肉注射可有效地扩张宫颈,降低宫腔镜手术操作的难度和并发症的危险。

Objective To compare the different between phloroglucinol and misoprostol on cervical dilation before hysteroscopic operation.Methods 96 women who needed hysteroscopic operation were randomly divided into two groups.80mg Phloroglucinol were muscular injected 30 minutes before hysteroscopy in group I（47 patients）,and 0.4mg Misoprostol were vaginal supposed 6-12 hours before hysteroscopy in group II（39 patients）.Cervical response,outcome,and complications of operative hysteroscopy and side effects were assessed.Results The cervical dilation non-estimated by 9’ Hegar dilator was 89.36% in group I,and 81.63% in group II.In group I,no complication was found.Conclusion The use of Phloroglucinol before hysteroscopy can reduce the need for cervical dilation,facilitate hysteroscopy and minimized cervical complications.