摘要
以硫酸肼为原料合成了氨基硫脲,以苯甲醛与乙酸酐为原料合成了肉桂酸,再由氨基硫脲与肉桂酸反应生成了一种新型取代噻二唑(2-氨基-5-苯乙烯基-1,3,4-噻二唑).3,4-噻二唑类化合物是含有N、S原子的五元杂环化合物,具有重要的化学和生物应用价值.目标产物及中间体的结构均经IR得以确定.
1,3,4-thiadiazole compounds have an important chemical and biological value , which contain N, S atoms of five-membered heterocycle compounds. In this paper, a novel substituted thiadiazole （2-amino-5-cinnamyl-1,3,4-thiadiazole） was synthesised. It is obtained by the reaction of thiosemicarbazide and cinnamic acid. Thiosemicarbazide is synthesized from sulfuric hydrazine. Cinnamic acid is synthesized from benzaldehyde and acetic anhydride. The structure of the object and intermediates were all confirmed by IR.
出处
《陕西科技大学学报（自然科学版）》
2010年第3期44-46,共3页
Journal of Shaanxi University of Science & Technology
关键词
1
3
4-噻二唑
肉桂酸
氨基硫脲
1
3
4-thiadizole
cinnamic acid
thiosemicarbazide
