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染料木素的药代动力学研究 被引量：2

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摘要 总结了国内外近5年有关染料木素的药代动力学研究资料,从吸收、分布、代谢、排泄四个方面进行归纳分析,以指导临床合理用药。
作者 赵绿英 黄红林
机构地区 南华大学药物药理研究所
出处 《中国医药指南》 2010年第20期227-229,共3页 Guide of China Medicine
关键词 染料木素 药代动力学
分类号 R969.1 [医药卫生—药理学]
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参考文献2

二级参考文献18

  • 1周四元,梅其炳,杨兴斌,李欣,胡玉珍,王剑波.染料木黄酮在Beagle犬体内的药代动力学[J].药学学报,2003,38(9):646-649. 被引量：6
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共引文献14

同被引文献16

  • 1刘莉,李鑫,刘丰,邓晓威.大豆异黄酮对代谢综合征模型大鼠抗动脉粥样硬化作用的机制[J].中国动脉硬化杂志,2008,16(12):928-932. 被引量：9
  • 2黄平,周宏灏.雌激素合成及代谢酶与乳腺癌易感性的研究[J].肿瘤学杂志,2004,10(4):267-270. 被引量：6
  • 3FUJIMAKI S, HAYASHI K. Soy isoflavones and breast cancer risk in Japan [ J ]. Journal of the National Cancer Institute, 2003,95 ( 24 ) : 1881 - 1882.
  • 4STEINER C, ARNOULD S, SCALBERT A, et al. Isoflavones and the prevention of breast and prostate cancer: new perspectives opened by nutrigenomics [ J]. British Journal of Nutrition ,2008,99:78 - 108.
  • 5DUFFY C, PEREZ K, PARTRIDGE A. Implications of phytoestrogen intake for breast cancer[J]. A Canc- er Journal for Clinicians,2007,57 ( 5 ) : 260 - 277.
  • 6TAYLOR C K, LEVY R M,ELLIOTT J C, et al. The effect of genistein aglycone on cancer and cancer risk: a review of in vitro, preclinical, and clinical studies [J]. Nutrition Reviews ,2009,67(7 ) :398 -415.
  • 7YANG Zhen, ZHU Wei, GAO Song, et al. Simultane- ous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC- MS/MS method:application to an oral bioavailability study of genistein in mice [ J ]. Journal Pharmaceutical Biomedical Analysis ,2010,53 ( 1 ) :81 -89.
  • 8ZHANG Yan, SONG T T, CUNNICK J E, et al. Daid- zein and genistein glucuronides in vitro are weakly es- trogenic and activate human natural killer cells at nu- tritionally relevant concentrations [ J ]. The Journal of Nutrition, 1999,129 ( 2 ) :399 - 405.
  • 9PUGAZHENDHI D ,WATSON K A ,MILLS S, et al.Effect of sulphation on the oestrogen agonist activity of the phytoestrogens genistein and daidzein in MCF- 7 human breast cancer cells [ J ]. Journal Endocrinol, 2008,197(3) :503 -515.
  • 10YUAN Bo, WANG Ling-lan, JIN Yi, et al. Role of metabolism in the effects of genistein and its phase II conjugates on the growth of human breast cell lines [ J ]. The AAPS Journal, 2012,14 ( 2 ) : 329 - 344.

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中国医药指南
2010年 第20期

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