高龄尿毒症患者血液透析滤过的临床探讨被引量：5

The clinical study of hemodiafiItration on elder patients with chronic renal failure

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摘要目的比较75岁以上慢性肾衰竭患者行血液透析(HD)及血液透析滤过(HDF)的可行性和有效性。方法将40例75岁以上慢性肾衰竭患者随机分为2组,A组(HD组)应用每周3次标准HD治疗;B组(HDF组)行每周1次常规标准HD治疗和每周2次HDF治疗。比较2组患者治疗前及治疗12周后甲状旁腺素(iPTH)、血压控制、贫血情况,观察治疗期间心血管并发症发生情况。结果 B组患者iPTH、血磷清除、平均动脉压下降更加显著,贫血纠正优于A组,低血压、心绞痛、心律失常、心衰的发生率明显降低。结论 HD及HDF是治疗高龄(≥75岁)慢性肾衰竭患者的有效手段。血液透析滤过对老年尿毒症患者有较好的心血管稳定性,值得临床推广。 Objective To observe the feasibility and effects of HD and HDF on older patients exceed 75 years old.Methods Fouty older patients with chronic renal failure were divided into 2 groups.The patients of group A were treated with HD thrice weekly and those of group B were treated with HDF twice in addition to HD weekly.IPTH,blood pressure,anaemic and the incidence of cardiovascu1ar events during treatment and 12 weeks posttreament was evaluated.Results The iPTH,removing of phosphorus,mean arterial blood pressure and anaemic rectification of group B were better than that of control group.The occurrence of hypotension,angina pectoris,cardiac arrhythmia and heart failure were significantly decreased in HDF group compared with those in control group.Conclusion Hemodialysis and Hemodiafiltration are effective on older patients with chronic renal failure.HDF can offer cardiovascular stability on older haemodialysis patients and it＇s worth be spread in clinc.

作者解德琼杜一平刘牧朱磊周进

机构地区宜宾市第二人民医院

出处《基层医学论坛》 2010年第19期577-579,共3页 The Medical Forum

关键词老年人血液透析血液透析滤过心血管疾病 Elder Hemodialysis Hemodiafiltration Cardiovascu1ardiseases

分类号 R692.5 [医药卫生—泌尿科学]

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参考文献5

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二级参考文献21

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