摘要
以丙烯酸甲酯为起始原料,经硫化、胺解、氯环化三步得到5氯2正辛基4异噻唑啉3酮,总收率167%。以双酚F为主体,上述异噻唑啉酮为客体,质量比为4∶1,形成分子包合物。产物结构经IR、1HNMR确认,对7种微生物试验,其抑菌能力比同类产品GathonCG大5~10倍。
The novel industry bactericide is a clathrate which is composed of 5 chloro 2 n octyl 4 isothiazolin 3 one and 4,4′ dihydroxydiphenylmethane.A reasonable synthesis route of first compound has been given out in this paper.It includes sulfidation,aminolysis and chloro cyclization,total yield is 16.7%.The product has identified by IR and 1 HNMR.The clathrate obtained is more effective in bactericidal potency than the same kind bactericide Gathon C G.
出处
《精细化工》
EI
CAS
CSCD
北大核心
1999年第1期4-7,共4页
Fine Chemicals
关键词
异噻唑啉酮
双酚F
杀菌剂
农药
有机杀菌剂
isothiazolinone
4,4′ dihydroxyldiphenylmethane
clathrate
bactericide