α-呋喃甲醇羧酸酯的合成研究

Synthesis of α Furfuryl Carboxylates

以α呋喃甲醇为基本原料，通过（１）吡啶／酰氯、（２）４二甲氨基吡啶／酸酐／无水碳酸氢钠、（３）４吡咯烷基吡啶／酸酐／无水碳酸氢钠三种方法，分别合成了α呋喃甲醇的乙酸酯、丙酸酯、丁酸酯、戊酸酯和己酸酯。结果表明：方法２和３中各产物的收率比方法１约高７％～２０％；方法２和３中产物收率和含量相近，收率８６．８％～９４．５％，含量均高于９９％。所合成的５个α呋喃甲醇酯的香气特征为带有轻微甜香的水果芳香。

The five α furfuryl carboxylates (i.e.,acetate,propionate,butyrate,valerate and hexanoate)were synthesized separately from α furfuryl alcohol by the following three methods:(1) acyl chlorides/pyridine;(2)4 dimethylaminopyridine/carboxylic anhydrides/sodium hydrogen carbonate anhydrous;(3)4 pyrrolidinopyridine/carboxylic anhydrides/sodium hydrogen carbonate anhydrous.The results indicated that the yields of the five α furfuryl esters in the method 2 and 3 are higher by about 7% to 20% than the method 1,and the yields and purities of the above five esters in the method 2 are similar to the method 3 (yields:86.8% to 94.5%;purities:>99%).The flavor characteristics of the five α furfuryl esters are fruity aromatic odor with light sweet.