间-四对甲氧基苯基卟啉的合成

Synthesis of meso Tetramethoxyphenyl Porphyrin

采用Ｖ（吡咯）∶Ｖ（对甲氧基苯甲醛）＝１∶１．７６的混合物为原料，在二甲苯溶剂中，以２％（ｗ）的氯乙酸为催化剂，在常压和１４２℃下合成了间四对甲氧基苯基卟啉。经重结晶和Ａｌ２Ｏ３柱层析，得紫红色结晶产品，产率２３．６％。经可见吸收光谱分析知，在氯仿介质中有６个大的吸收峰，波长分别为４２１．３、４８７．２、５１８．１、５５５．２、５９３．６和６５０．３ｎｍ，证明该卟啉是一种较四苯基卟啉更有效的光吸收剂。

meso Tetramethoxyphenyl porphyrin has been prepared catalyzed by 2% chloroacetic acid in xylene solvent ,using pyrrol and para hydroxy benzaldehyde as reactants which volume ratio is 1∶1.76.The yield of the pure purple product achieved by recrystallization in mixed organic solvent and separation with Al 2O 3 column chromatography was 23.6%.The absorption spectrum of the product was determined by visible spectrophotometer,in which there are 6 maxium peaks located at 421.3,487.2,518.1,555.2,593.6 and 650.3 nm,and proved that it is a more photoactive substance than tetraphenyl porphyrin .