无锡地区生殖道感染解脲脲支原体、人支原体分子流行病学研究

Molecular Epidemiology of Ureaplasma urealytium and Mycoplasma hominis in Male and Female Patients with Reproductive-tract Infection in Wuxi

目的了解无锡地区男女性生殖道感染者解脲脲支原体(Uu)、人支原体(Mh)感染状况。方法收集2007-2008年医院就诊的1580例男女性生殖道感染者病灶部拭子标本,应用套式聚合酶链反应(nPCR)技术进行Uu、Mh 2种支原体核酸检测。结果 1580例男女性生殖道感染者Uu、Mh 2种支原体阳性率分别为42.8%、19.2%,支原体总阳性率达50.9%;其中女性Uu、Mh 2种支原体的检出率明显高于男性。结论无锡地区2007-2008年男女性生殖道感染者中支原体感染率高,且已构成流行。

OBJECTIVE To investigate the infective status of Ureaplasma urealyticum and Mycoplasma hominis among the reproductive-tract infected patients in Wuxi.METHODS A total of 1580 swab specimens of reproductive-tract infected patients,who were treated in Wuxi People′s Hospital from 2007 to 2008,had been gathered.Using the technology of nested Polymerase Chain Reaction（nPCR）,the genes of U.urealyticum and M.hominis were detected.RESULTS The positive rate of U.urealyticum and M.hominis was 42.8% and 19.2%,respectively.A total infective ratio was 50.9% from 1580 specimens,and the positive rate in females was remarkably higher than that in males.CONCLUSION The infective rate of U.urealyticum and M.hominis among reproductive-tract infected patients in Wuxi is high from 2007 to 2008,which easy to be epeclencic.