T细胞特异Elf-1转录因子的研究进展

The progress of the special transcription factor of T lymphocytes, Elf-1

Elf-1是Ets转录因子家族的一员,参与细胞增殖、分化和恶变等生理病理过程.文章对Elf-1与T细胞分化发育、肿瘤及自身免疫性疾病的关系进行综述.

Elf-1 （E74-like factor 1） is a member of Ets transcription factor family,which participated in physiological and pathological process of cells proliferation,differentiation and tumorigenesis. In this review,we summarize that Elf-1 is related to T cell differentiation and development,tumor and autoimmune disease.