高通量血液透析与常规血液透析疗效比较

目的比较高通量血液透析与常规血液透析的临床疗效。方法回顾性分析我院近年来收治的45例行维持性血液透析患者的临床资料,根据透析方法及透析器的不同,将患者随机分为两组,高通量血液透析(HPD)组23例,常规血液透析(CHD)组22例,比较两组患者的疗效差异。结果 HPD组各项检测指标透析前后下降率为BUN值为(69.2±5.3)%,SCr值为(63.1±5.4)%,P值为(58.1±15.9)%,β2-MG值为(1.39±0.62)%,PTH值为(71.3±15.3)%;CHD组BUN值为(68.8±4.9)%,SCr值为(62.8±5.9)%,P值为(56.2±14.7)%,β2-MG值为(33.5±8.4)%,PTH值为(16.5±9.4)%;两组患者血液透析前后的BUN、SCr下降率比较无明显差异性,而磷(P)、β2-微球蛋白(β2-MG),甲状旁腺素(PTH)比较,有显著性差异。结论高通量血液透析治疗终末期肾病患者与常规血液透析比较,疗效更为确切,值得临床推广使用。

Objective To compare clinical efficacy of the high-flux hemodialysis and conventional hemodialysis.Methods Clinical data of 45 patients of routine maintenance hemodialysis admitted to our hospital in recent years were retrospectively analyzed,according to dialysis methods and different dialyzer,the patients were randomly divided into two groups,high-flux hemodialysis（HPD） section 23 cases,conventional hemodialysis（CHD） group of 22 patients the efficacy of two groups were compared.Results HPD group of indicators of the detection rate of decline before and after dialysis for：BUN value（69.2 ± 5.3）%,SCr value（63.1 ± 5.4）%,P value（58.1 ± 15.9）%,β2-MG value（1.39 ± 0.62）%,PTH values（71.3±15.3）%;CHD group BUN values（68.8 ± 4.9）%,SCr value（62.8 ± 5.9）%,P value（56.2 ± 14.7）%,β2 value of a MG to（33.5 ± 8.4）%,PTH values（16.5 ± 9.4）%;the two groups before and after hemodialysis in patients with BUN,SCr was no significant difference in rate of decline,whereas phosphorus（P）,β2microglobulin（β2-MG）,parathyroid hormone（PTH） compared to a significant difference.Conclusion The high-flux hemodialysis for end-stage renal disease compared with conventional hemodialysis,efficacy more accurately,it is worth for clinical use.