摘要
报道了苯巴比妥聚乙二醇滴丸的制备及其在家兔体内生物利用度（荧光偏振免疫分析法）。结果表明该滴丸与片剂的Tmax、Cmax、AUC值均有显著性差异（P＜0．01），滴丸对片剂的生物利用度为316％。
Phenobarbital pills were prepared and its bioavailability in rabbits was tested. The plasmaconcentrations of phenobarbital were determined by FPIA. The results showed there was statistic differ-ence between the pills and tablets in Tmax, Cmax and AUC (P < 0.01 ). The relative bioavailabitity of thepills was 3l6 %.
出处
《西北药学杂志》
CAS
1999年第1期16-17,共2页
Northwest Pharmaceutical Journal
关键词
苯巴比妥
滴丸
生物利用度
聚乙二醇
Phenobarbital
pills
polyethylene glycol
bioavailability
