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MicroRNA与糖尿病

MicroRNA and diabetes
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摘要 MicroRNA是一种非编码的小分子RNA,在基因表达调控中发挥重要作用。最新研究表明micro RNA与胰岛素生成、胰岛素分泌、胰岛素作用及胰岛的发育均密切相关,在糖尿病的发病中可能起着必不可少的作用。深入研究microRNA可能为糖尿病的诊断和治疗带来全新的方法。 MicroRNA is a class of short non-coding RNA that has important role in gene regulation.Recent studies have demonstrated that microRNA closely relates to insulin production,secretion,action,and pancreatic islet development,which is crucial for the pathogenesis of diabetes.It has been suggested that microRNA may have potential diagnostic and therapeutic applications in diabetes.
作者 刘细玉 李一君 周智广
机构地区 中南大学湘雅二医院内分泌科中南大学代谢内分泌研究所
出处 《国际病理科学与临床杂志》 CAS 2010年第3期216-219,共4页 Journal of International Pathology and Clinical Medicine
基金 国家973项目(2009CB825605 2006CB503901)~~
关键词 MICRORNA 糖尿病 胰岛素 microRNA diabetes insulin
分类号 R587.1 [医药卫生—内分泌]
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参考文献26

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国际病理科学与临床杂志
2010年 第3期

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