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西立伐他汀钠 被引量:2

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摘要 西立伐他汀钠,1997年4月14日以Lipobay在英国注册上市。最近以商品名Baycol在美国获准上市。它是新的HMGCoA还原酶抑制剂,用于治疗对限制饮食效果不明显的原发性高胆固醇血症(Ⅱa型和Ⅱb型)。【药效学】〔1,2〕本品可显著降低总胆固...
出处 《中国新药杂志》 CAS CSCD 1999年第2期120-121,共2页 Chinese Journal of New Drugs
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  • 1朱汝锦.辛伐他汀的药理学及其对高胆固醇血症的治疗[J].国外医药(抗生素分册),1996,17(6):457-465. 被引量:3
  • 2陈新谦 金有豫.新编药物学[M](第14版)[M].北京:人民卫生出版社,1998.78.
  • 3Straznicky NE, Howes LG, Lam W, et al. Effects of pravastatin on cardiovascular reactivity to norepine phrine and angiotensin Ⅱ in patients with hypercholesterrolemia and systemic hypertension[J]. Am J Cardio, 1995,75:582
  • 4Treasure CB, Klein JL, Weintraub WS, et al. Benifical effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease [J]. NEJM, 1995,332(8):481
  • 5Andrews TC, Raby K, Barry J, et al. Effect of cholesterol reduction on myocardial is chemia in patients with coronary disease[J]. Circulation, 1997,95:324
  • 6Robert S, Rosenson, Christine C, et al. Antiatherrothrombotic properties of statins: Implications for cardiovascular event reduction[J]. JAMA, 1998, 279(20):1643
  • 7Corsini A, Raiteri M, Soma M, et al. Simvastatin but not pravastation inhibits the proliferation of rat aorta myocytes[J]. Pharm Res, 1991,23(2):173
  • 8Kempen HJM, Vemeer M, Dewit E, et al. Provastatins inhibit cholesterol ester accummulation in human monocyte-derived macrophages[J]. Arteropscler Thrpmb, 1991,11:146
  • 9Kimura M, Kurose I, Russell J, et al. Effects of fluvastatin on leukocyte-endothelial cell adhesion in hypercholesterolemia rats[J]. Arterioscler Thromb Vasc Biol, 1997,17:1521
  • 10陈新谦,金有豫主编.新编药物学 [M].第 14版.北京:人民卫生出版社,1998: 297.

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