摘要
目的采用颈动脉超声监测阿托伐他汀治疗无症状颈动脉斑块的疗效和安全性,观察超声检查对颈动脉斑块的诊断价值。方法运用多普勒彩超检查对缺血性血管疾病进行筛查,发现颈动脉斑块者,随机分为两组,治疗组病人给予阿托伐他汀(10mg,po,qd×24周)后予以复查颈动脉彩超,并与对照组相比较。结果通过颈动脉彩超检查,与对照组相比,治疗组经阿托伐他汀治疗后,颈动脉斑块数目减少,斑块面积明显缩小,颈动脉内中膜厚度(IMT)减小。两组比较差异有显著意义(P<0.05)。结论阿托伐他汀治疗颈动脉斑块疗效显著,多普勒彩超检查对颈动脉斑块的诊断、预防及治疗有重要临床指导意义。
Objective Carotid artery ultrasound to monitor use of atorvastatin treatment of asymptomatic carotid artery plaque effi cacy and safety,observe the ultrasound examination the diagnosis of carotid artery plaque.Methods The use of Doppler color Doppler ultrasound examination of ischemic vascular disease screening and found that carotid plaques were randomly divided into two groups,treatment group of patients given atorvastatin (10mg,po,qd × 24 weeks) to be reviewed after the neckartery color Doppler ultrasound,and compared with the control group. Results Through the carotid artery color Doppler ultrasound examination,as compared with the control group,treatment group after atorvastatin treatment,reducing the number of carotid artery plaque,plaque area significantly reduced carotid artery intima-media thickness (IMT) decreased. Difference between the two groups was significant (P〈0.05).Conclusion Atorvastatin treatment efficacy of carotid artery plaque significantly,Doppler color Doppler ultrasound examination in the diagnosis of carotid artery plaque,prevention and treatment have important clinical significance.
出处
《当代医学》
2010年第19期12-13,共2页
Contemporary Medicine