淫羊藿对生殖及内分泌系统的药理学研究进展

Pharmacological Progress of Epimedium on Reproductive and Endocrine System

对生殖及内分泌系统的药理作用是淫羊藿研究的主要内容之一,也是其临床疗效的重要基础,迄今已积累了较多文献。多数报道显示淫羊藿既有性激素样作用,也可作用于丘脑-垂体-性腺/肾上腺轴的一个或多个环节,从而上调性激素水平;对性器官、生殖细胞、性功能等也有一定影响。但不同或相反结论亦见诸报道,因此仍需切实深入的研究,以阐明其作用机理,并拓展新的应用领域。

The pharmacological role on reproductive and endocrine system is one of the main contents in the research of epimedium,and also the important basis for its clinical efficacy.Most reports show epimedium has both sex hormone-like effect and effect on hypothalamus-pituitary-gonadal/adrenal axis to increase sex hormone levels.It also has effect on sex organ,generative cells and sexual function.However,some different or contrary conclusions have been reported,so more researches need to be done to explain its mechanism of action,and to explore new application fields.