腹腔镜术辅以化瘀消癥汤治疗子宫内膜异位症合并不孕临床研究

Clinical Study on Endometriosis-induced Infertility Treated by Laparoscopy Combined with Resolving Blood Stasis and Abdominal Mass Decoction

目的:探讨腹腔镜保守性手术后用中药治疗子宫内膜异位症合并不孕的临床疗效。方法:60例随机分为中药组35例和西药组25例,分别用中药化瘀消癥汤及西药孕三烯酮治疗,比较术后应用化瘀消癥汤和孕三烯酮的疗效、妊娠率、不良反应及复发情况。结果:两组症状都得到不同程度的缓解,两组总有效率分别为85.72%和84.00%,差异无统计学意义(P>0.05),中药组术后1年内妊娠率为60.00%,西药组术后1年内妊娠率为32.00%,两组比较有显著性差异(P<0.05)。中药组及西药组复发率分别为11.42%和12.00%,差异无统计学意义(P>0.05)。结论:中药化瘀消癥汤用于盆腔子宫内膜异位症保守性手术后的巩固治疗可预防和减少复发,调节内分泌,提高妊娠率,且不良反应小。

Objective：To study the clinical value of laparoscopic operation combined with HuaYuXiaoZheng Decoction therapy on endometriosis associated with infertility.Methods：From March 2008 to Octobor 2009,60 cases dignosed endometriosis（EM） associated with infertility who were underwent laparoscopic operations were divided into 2 groups at random,treated with HuaYuXiaoZheng Decoction group （the study group,n=35） and treated with gestrinone group（the control group,n=25）.Results：The totle effective rate had no significant difference（P0.05） between the study group（85.71%） and the control group（84.00%）.The pregnancy rate of the study group（60.0%） was significantly higher than that of group B （32.00%）（P0.05）.The recurrence rate had no significant difference（P0.05）between the study group（11.42%） and the control group（12%）.Conclusion：Laparoscopic operation can be used in the treatment of endometriosis associated with infertility.Combined with post-operative TCM therapy is an effective recipe in treating endometriosis.