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大鼠全脑缺血诱发癫痫模型的建立 被引量:5

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摘要 目的:建立一个简单,创伤少大鼠癫痫模型,以期使该类型癫痫的研究更符合临床病理情况。方法:利用胸部挤压器造成暂时性缺血,复苏后声音诱发癫痫发作,记录其发作情况,分析脑电图变化,并作实验性治疗。结果:该模型成功率为43%,发作形式类似遗传性易感大鼠(GEPR),脑电图符合癫痫诊断,实验治疗效果明显。结论:全脑缺血诱发大鼠癫痫模型操作简便,制作成功率高,接近临床病理情况。
出处 《立体定向和功能性神经外科杂志》 1999年第1期8-11,共4页 Chinese Journal of Stereotactic and Functional Neurosurgery
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