我院重症监护病房患者深部真菌感染病例临床分析

Analysis of systemic fungal infections in ICU in our hospital

目的:分析我院重症监护病房(ICU)患者深部真菌感染的危险因素,并探讨其控制对策。方法:收集我院55例近2年被诊断为ICU深部真菌感染患者的临床资料,分析患者的基础疾病、住院时间、真菌感染部位、真菌病原学资料、药物的应用情况、侵入性治疗方法、治疗转归等。结果:55例ICU深部真菌感染患者中,以白念珠菌及热带念珠菌为主,其中白念珠菌占45.45%,热带念珠菌占10.91%;感染部位以呼吸道感染最常见,占33.77%,其次为尿路感染,占32.47%;住院时间越长及侵入性操作与真菌感染发生的几率越大;药物的总有效率为60%。结论:ICU患者深部真菌感染的发病率较高,应减少或避免可能导致真菌感染的各种危险因素,积极采取有效的防范措施。

Objective： To analyze the risk factors of deep fungal infections in patients in ICU of our hosp ital,and to explore the control strategy of these infections.Methods： Fifty-five patients in ICU who were diagnosed as deep fungal infections in the last 2 years were involved.The basic disease of patients,length of stay,position of fungal infection,etiology data,application of drug,invading therapies,the result of treatment and so on were analyzed.Results： In the 55 patients with deep fungal infection,the major pathogens were Candida tropicalis and Blastomyces albicansa.Candida ropicalis caused 45.45% and Blastomyces albicans caused 10.91% of the infections.The respiratory tract was the most common infected location（33.77%）;the urinary tract was the second infected location（32.47%）.Various risk factors increased the chance of deep fungal infections.The effective rate was 60%.Conclusion： The incidence of deep fungal infections in ICU is high,so we should take effective control measures to reduce and avoid these risk factors.