托烷司琼预防腹腔镜术后恶心呕吐的效果观察

目的观察托烷司琼预防腹腔镜术后恶心呕吐的效果。方法选择2006年9月-2009年12月50例行腹腔镜手术的患者,随机分为实验组和对照组,每组25例。两组均给予气管内插管全身麻醉,实验组拔管前30min静脉注射托烷司琼5mg,对照组拔管前30min静脉注射胃复安10mg。比较两组患者术后恶心呕吐程度及发生率。结果两组患者恶心呕吐程度及发生率比较,均P<0.05,差异具有统计学意义,实验组恶心呕吐程度轻于对照组、恶心呕吐发生率低于对照组。结论托烷司琼能有效减轻腹腔镜术后恶心呕吐程度、降低恶心呕吐的发生率。

Objective To investigate the curative effect of Tropisetron on nausea and vomiting after laparoscopic surgery. Methods 50 patients undergoing laparoscopic surgery under general anesthesia from September 2006 to December of 2009 were randomized into the experimental group and the control group in equal number： the former group receiving 30min intravenous injection of 5mg Tropisetron before extubation while the latter 30 rain intravenous injection of 10 mg metoelopramide before extubation. The degree and incidence of postoperative nausea and vomiting were observed and compared between the two groups. Result The degree and the incidence of nausea and vomiting in the experimental group were significantly lower than those of control group （P 〈 0.05）. Conclusion Tropisetron can reduce the degree of postoperative nausea and vomiting and incidence.