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罗格列酮对早期糖尿病肾病患者肾脏的保护作用

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摘要 目的:探讨胰岛素增敏剂罗格列酮对糖尿病患者肾脏的保护作用。方法:选取早期糖尿病肾病患者60例,治疗组在原控制血糖方案基础上加用罗格列酮4mg/日,对照组在原控制血糖方案基础上加用二甲双胍观察3个月,观察治疗效果和尿微量白蛋白排泄率(UAER)、C-反应蛋白(CRP)、C肽等。结果:治疗组治疗效果明显高于对照组,并且患者HbA1c(%)、UAER(μg/分)、CRP(mg/L)、C肽(mg/L)下降及HDL-C上升,具有统计学意义。结论:罗格列酮在降糖的同时亦可减少尿蛋白排泄,有一定的肾脏保护作用。
作者 刘学军
出处 《中国社区医师(医学专业)》 2010年第21期48-48,共1页
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