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腹腔内注射腺苷对大鼠海马区c-fos表达的影响

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摘要 目的研究腹腔内注射腺苷对大鼠海马区c-fos蛋白表达的影响。方法腹腔内注射腺苷和其非特异性受体阻断剂茶碱,采用Fos免疫组织化学染色(ABC法),观察c-fos蛋白在海马区内的分布情况。结果注入腺苷后大鼠海马区的c-fos蛋白表达与注入生理盐水相比明显增加,注入茶碱后大鼠海马区的c-fos蛋白表达与对照组相比无显著变化。结论腺苷能促进海马区c-fos蛋白的表达,腺苷在海马区内对调节睡眠可能有重要作用。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2010年第13期1822-1823,共2页 Chinese Journal of Gerontology
基金 长春市科技局资助课题〔长科技合(2008255)号-08YJ38〕
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参考文献12

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