针刺治疗中风失语症疗效的系统评价

Acupuncture therapy for apoplectic aphasia:a systematic review

目的:评价针刺治疗中风失语症的临床疗效。方法:采用循证医学(Cochrance)系统评价的方法,逐一评价纳入研究的质量,提取有效数据,采用RevMan5.0软件进行Meta分析。结果:共纳入11篇文章,756例中风失语症患者。Meta分析结果显示:针刺组与语言训练组比较,痊愈率差异有统计学意义[RR=1.74,95%CI(1.10,2.74),P=0.02];针刺结合语言训练组与语言训练组比较,其痊愈率[RR=3.01,95%CI(1.81,5.01),P<0.0001]、语言功能评分[WMD=10.54,95%CI(7.86,13.21),P<0.00001]、口语表达水平[WMD=8.86,95%CI(7.38,10.35),P<0.00001],差异均有统计学意义。结论:针刺(或结合语言训练)治疗中风失语症有效。但纳入文献质量不高,尚期待高质量的试验提供高质量证据。

Objective To assess the therapeutic effect of acupuncture for apoplectic aphasia. Methods A systematic review of the relevant randomized controlled trials （RCTs） of acupuncture for apoplectic aphasia was performed with Cochrance system assessment methods. The quality of researches was reviewed one by one, and data was extracted by two reviewers independently. Meta-analysis was conducted with the assistance of RevMan 5.0 software. Results Eleven randomized controlled trials （RCTs） involving 756 patients were included. Meta-analysis indicated that there was statistical difference between acupuncture and language training groups on cured rate with ERR=I. 74, 95%CI（1.10,2.74）, P= 0. 021 at the end of treatment. However, acupuncture combined language training group was statistically superior to language training group on cured rate with [RR = 3.01,95 % CI（ 1.81, 5.01） ,P〈0. 000 1], language function score with [WMD=10.54, 95%CI（7.86,13.21）, P〈0. 000 01], oral expressionwith[WMD=8.86, 95% CI（7.38, 10.35）,P〈0.00001]. Conclusion It is approved that acupuncture （or acupuncture combined language training） is effective for apoplectic aphasia. But the quality of inclusive literature is low. Therefore, more RCTs of high methodological quality is requested to be carried out.