丝裂霉素C预防翼状胬肉复发

Effect of mitomycin C on preventing pterygium recurrence during excision

目的 探讨翼状胬肉切除术中应用丝裂霉素Ｃ减少胬肉复发的效果。方法 在翼状胬肉切除术中应用丝裂霉素Ｃ（０．２ｇ·Ｌ－ １，５ｍ ｉｎ），术后随访６～１２ｍ ｏ，平均随访１０ｍ ｏ。结果 ２１ 例２４ 眼中２３ 眼治愈，１ 眼复发。术中、术后及随访期间未发现严重的眼部并发症及全身毒性反应。结论 翼状胬肉切除术中应用丝裂霉素Ｃ是一种安全有效减少胬肉术后复发的治疗方法。

Objective To study the effect of mitomycin C on preventing pterygium recurrence during excision. Methods Mitomycin C(0.2g·L -1 ,five minutes) was used in the excision of pterygium. The average period of follow up was about 10 months. Results Only one of the 24 eyes in 12 patients with pterygium performed on excision with mitomycin C had the attack of old disease. Neither serious ocular complications nor systemic toxicities were noted in or after the operation. Conclusion The use of mitomycin C during the excision can prevent pterygium recurrence with safe and high effect.