摘要
目的:探讨多靶点治疗狼疮性肾炎的临床疗效。方法:回顾性分析本院收治的狼疮性肾炎患者46例的临床资料,依据肾炎治疗方式分为普通观察组(23例)和多靶点对照组(23例)。普通观察组在整个治疗过程中给予环磷酰胺加入0.9%氯化钠注射液中静滴或静注。而多靶点对照组采用多靶点+强的松药物,并在治疗中加用环磷酰胺(CTX)。结果:多靶点对照组治疗效果优于普通观察组,多靶点对照组总治愈率为91.3%,普通观察组治愈率为34.78%。结论:在整个治疗过程中运用多靶点+强的松的稳固治疗,为狼疮性肾炎患者减轻了疾病上的疼痛,治愈率高,安全性大。所以,多靶点治疗在临床上是有效、可观的治疗方法,是值得临床推广的一种治疗方法。
Objective:To investigate the clinical effect of the multi-target treatment of lupus nephritis.Methods:Retrospective analysis of patients with lupus nephritis were treated 46 cases of clinical data,based on general observation of nephritis were divided into treatment group (23 cases) patients,and multi-target control group (23 cases) patients.General observation group in the whole course of treatment for cyclophosphamide 0.9% sodium chloride injection or intravenous infusion. The multi-target control group,multi-target and prednisone drug, the treatment was added in CTX.Results:The multi-target control group was superior to the observation group,multi-target control group cure rate was 91.3% ,general observation group the cure rate was 34.78%.Conclusion:The use of the entire course of treatment,the stability of multi-target and prednisone therapy for patients with lupus nephritis to reduce the pain of disease,high cure rate,safety,great.Therefore,the multitarget therapy is clinically effective and substantial treatment is worth promoting as a medical treatment.
出处
《中国当代医药》
2010年第20期31-32,共2页
China Modern Medicine
关键词
多靶点
狼疮性肾炎
安全性大
Multi-target
Lupus nephritis
Safety of large