期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

^(18)F-FDG PET/CT在结外淋巴瘤诊治中的临床应用 被引量：3

CLINICAL APPLICATION OF ^(18)F-FDG PET/CT SCANNING IN THE DIAGNOSIS AND TREATMENT OF EXTRANODAL LYMPHOMA
下载PDF
导出
摘要 目的探讨18F-FDG PET/CT对结外淋巴瘤诊断和疗效判断的临床意义。方法对16例临床评价和18F-FDG PET/CT拟诊结外淋巴瘤病人进行手术活组织病理学检查,并在治疗后应用以上2种方法进行疗效判断。结果临床评价拟诊结外淋巴瘤10例(10/16),PET/CT拟诊结外淋巴瘤16例(16/16),手术活检病理确诊14例;治疗后临床评价提示4例有肿瘤残余,PET/CT提示2例有肿瘤残余。结论 PET/CT对结外淋巴瘤的诊断和疗效判断具有重要价值。 Objective To assess the clinical value of 18F-FDG PET/CT scanning in the diagnosis and treatment for patients with extranodal lymphoma（ENL）. Methods A histologic examination was done in 16 patients diagnosed clinically and by 18F-FDG PET/CT as having ENL.After therapy,the efficacy was evaluated by 18F-FDG PET/CT. Results Clinically,10（10/16） cases were diagnosed as ENL;16（16/16） by PET/CT;14 were confirmed pathologically.Post-therapeutically,clinical assessment was suggestive of residual tumor in four cases,and PET/CT in two with residual tumor. Conclusion PET/CT is of great value in judgement of the diagnosis and therapeutic efficacy of ENL.
作者 史春雷 王玲 黄梅娟 李颖 袁成录
机构地区 青岛市中心医院血液科
出处 《齐鲁医学杂志》 2010年第5期394-395,398,共3页 Medical Journal of Qilu
关键词 体层摄影术 发射型计算机 淋巴瘤 诊断 tomography emission-computed lymphoma diagnosis
分类号 R814.42 [医药卫生—影像医学与核医学]
  • 相关文献

参考文献9

  • 1FREUDENBERG L S,ANTOCH G,SCHUTT P,et al.FDG-PET/CT in restaging ofpatients with lymphoma[J].Eur Jnucl Med Mol Imaging,2004,31(3):325-329.
  • 2张天泽 徐光炜.肿瘤学[M].天津：天津科学技术出版社,1996.1209.
  • 3KONIARIS L G,DDRUGAS G,KATZMAN P J,et al.Management of gastrointestinal lymphoma[J].J Am Coll Surg,2003,197(1):127-141.
  • 4AL-SHEMMARI S H,SAJNANI K P,AMEEN R M,et al.Primary gastrointestinal non-Hodgkin's lymphoma:treatment outcome[J].Clin Lymohoma,2003,4(2):99-103.
  • 5王艳丽,崔新建.PET-CT在肺癌诊断及分期中的应用进展[J].齐鲁医学杂志,2009,24(1):90-91. 被引量：9
  • 6BANGERTERr M,KOTZERKEJ.Positron emission tomography with 18-fluorodeoxygluucose in the staging and follow-up of lymphoma in the chest[J].Acta Oncol,1999,38(6):799-804.
  • 7JERUSALEM G,WARLAND V,NAJJAR F,et al.Whole-body 18F-FDG PET for the evaluation of patients with Hodgkin's disease and non-Hodgkin's lymphoma[J].Nucl Med Commun,1997,20(1):13-20.
  • 8叶任高.内科学[M]5版[M].北京:人民卫生出版社,2002.862.
  • 9SPAEPEN K,STROOBANTS S,DUPONT P,et al.Prognostic value of positron emission tomography with fluorine-18 fluorodeoxyglucose (18F-FDG) after first-line chemotherapy in non-Hodgkin's lymphoma:18F-FDG PET a valid alternative to conventional diagnostic methods[J].J Clin Oncol,2001,19:414-419.

二级参考文献12

  • 1林吉征,孙德宝,李颖端,李绍科,杨学东,路晓东.CT动态增强扫描对肺内孤立性小结节的鉴别诊断价值[J].青岛大学医学院学报,2006,42(4):312-314. 被引量：5
  • 2SWENSEN S J, VIGGIANO R W, MIDTHUN D E, et al. Lung nodule enhancement at CT: multieenter study[J]. Radiology, 2000,214(1) :73-80.
  • 3SHON I H, O'DOHERTY M J, MAISEY M N, et al. Positron emission tomography in lung cancer [J] .Semin Nucl Ued, 2002,32(4):240-271.
  • 4PRAUER H W, WEBER W A, ROMER W, et al. Controlled prospective study of positron emission tomography using the glucose analogue [18f] fluorodeoxyglucose in the evaluation of pulmonary nodules[J]. Br J Surg, 1998,85(11) : 1506-1511.
  • 5GOULD M K, MACLEAN C C, KUSCHNER W G, et al. Accuracy of positron emission tomography for diagnosis of pul monary nodules and mass lesions[J]. JAMA, 2001,285 (8) 914-924.
  • 6GOERRES G W, KAMEL E, SEIFERT B, et al. Accuracy of image coregistration of pulmonary lesions in patients with nonsmall cell lung cancer using 8n integrated PET/CT system[J], J Nucl Med, 2002,43(11) : 1469-1475.
  • 7SHIG S S, LEE K S, KIM Q T, et al. Non-small cell lung cancer: prospective comparison of integrated FDG PET/CT and CT alone for preoperative staging[J]. Radiology, 2005, 106(3): 1011-1019.
  • 8LARDINOIS D, WEDER W, HANY T F, et al. Staging of non-small cell lung cancer with integrated positron emission tomography and computed tomography[J]. N Engl J Med, 2003,348 (25): 2500-2507.
  • 9HALPERN B S, SCHIEPERS C, WEBER W A, et al. Presurgical staging of non-small cell lung cancer: positron emission tomography, integrated positron emission tomography/ CT, and software image fusion[J]. Chest, 2005, 128(4): 2289-2297.
  • 10ANTOCH G, STATTAUS J, NEMAT AT, et al. Non-small cell lung cancer:dual modality PET/CT in preoperative staging [J]. Radiology, 2003,229(2):526-533.

共引文献825

同被引文献37

  • 1王敏,李锦添,曾益新,侯景辉,林琼琼.Notch1、P21^(WAF1)和Involucrin在鼻咽癌组织中的表达及意义[J].癌症,2005,24(10):1230-1234. 被引量：10
  • 2KARANU F N, MURDOCH B, GALLACHER L, et al. The notch ligand jagged-1 represents a novel growth factor of hu- man hematopoietic stem cells[J]. Journal of Experimental Medicine, 2000,192(9) :1365-1372.
  • 3DUMORTIER A, WILSON A, MACDONALD H R, et al. Paradigms of notch signaling in mammals[J]. International Journal of Hematology, 2005,82 (4) : 277-284.
  • 4CHIARAMONTE R, BASILE A, TASSI E, et al. A wid, role for NOTCH1 signaling in acute leukemia[J].Cancer Let ters, 2005, 219(1):113-120.
  • 5GAO J, LIU J, FAN D, et al. Up-regulated expression of Notch1 and Jagged1 in human colon adenocarcinoma[J]. Pa thologie Biologic, 2011,59(6) :298-302.
  • 6ELLISEN L W, BIRD J, WEST D C, et al. TAN-l, the hu man homolog of the Drosophila notch gene, is broken by chro mosomal transloeations in T lymphoblastic neoplasms [J]. Cell, 1991,66(4) :649-661.
  • 7DORSCH M, ZHENG GANG, YOWE D, et al. Ectopic ex pression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease[J]. Blood, 2002,100(6) 2046-2055.
  • 8CULLION K, DRAHEIM K M, HERMANCE N, et al. Tar- geting the notch1 and mTOR pathways in a mouse T-ALL moclel[J]. Blood, 2009,113(24) :6172-6181.
  • 9JUNDT F, ANAGNOSTOPOULOS I, FC)RSTER R, et al. Activated notchl signaling promotes tumor cell proliferation and survival in hodgkin and anaplastic large cell lymphoma[J].Blood, 2002,99(9) :3398-3403.
  • 10BAUMG A RTNER A K, ZETTL A, CHOTT A, et al. High frequency of genetic aberrations in enteropathy-type T cell lymphoma[J]. Laboratory Investigation, 2003,83 (10) 1509-1516.

引证文献3

二级引证文献10

齐鲁医学杂志
2010年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部