部队在职干部代谢综合征药物治疗后生活方式干预的疗效观察

Life style intervention enhances medication effect on metabolic syndrome in army officers

目的加强个人生活方式干预可降低代谢综合征(metabolic syndrome,MS)的发病率,文中旨在探讨生活方式干预对部队MS患者药物治疗后疗效的影响。方法已接受药物治疗的部队MS患者96例,根据有无接受生活方式干预(改变饮食方式、有氧运动、戒烟限酒等)分为药物+生活方式干预组62例和单纯药物组34例。随访3个月,记录2组患者干预前、随访3月后的体重指数、腰围、血压、血脂和血糖资料,并对资料进行统计分析。结果药物+生活方式干预组3个月后体重、腰围、血脂、血糖、血压的达标率均优于单纯药物组(P<0.05或P<0.01)。结论坚持全面生活方式干预可明显提高MS患者药物治疗后的疗效。

Objective Lifestyle intervention can lower the risk of metabolic syndrome（MS）.This study aims to explore the effect of lifestyle intervention on MS after drug therapy in army officers.Methods A total of 96 army officers with MS were divided into a drug therapy group（n= 34） and a drug therapy ＋ lifestyle intervention group（n = 62）,the former treated by medication alone,while the latter both medication and intervention of individual lifestyles,which included change of dietary habit,increase of physical activity,cigarette cessation,and alcohol restriction.All were followed up for 3 months,their body mass index,waist circumference,blood pressure,blood glucose and blood lipid were obtained before and after the intervention and subjected to statistic analysis.Results At 3 months,the drug therapy ＋ lifestyle intervention group showed a significantly higher rate of improvement in body weight index,waist circumference,blood pressure,blood glucose and blood lipid than the drug therapy group（P0.05 or P0.01）.Conclusion Life style intervention can significantly improve the medication effect on MS in army officers.