地塞米松复合氟哌啶预防腹腔镜手术后病人恶心呕吐的疗效观察

Effective observation of dexamethasone combined with droperidol for preventing nausea and vomiting after laparoscopic operation

目的:观察地塞米松、氟哌啶、地塞米松+氟哌啶、生理盐水4组用药方式在预防腹腔镜手术后恶心、呕吐的疗效。方法:将120例病人随机分为4组(n=30),在麻醉诱导前分别经静脉注射地塞米松10mg(Ⅰ组)、氟哌啶2.5mg(Ⅱ组)、地塞米松10mg+氟哌啶2.5mg(Ⅲ组)和生理盐水对照组(Ⅳ组),观察术后病人恶心呕吐、发热、描述词量表评分情况。结果:Ⅰ组有利于降低术后发热率,Ⅱ组恶心、呕吐率下降(P<0.05),Ⅲ组发热率、描述词量表评分及呕吐次数明显下降(P<0.05)。结论:复合应用地塞米松+氟哌啶在预防腹腔镜手术后病人恶心呕吐和降低术后体温具有明显效果。

Objective ：To compare the effects of dexamethasone, droperidol,dexamethasone plus droperidol,normal saline for preventing nausea and vomiting after laparoscopic operation. Medthods：The patients were randomly divided into 4 groups, 30 cases in each group. Group I was given intravenous dexamethasone 10 rag,group II was given droperidol 2.5 rag,group III received dexamethasone 10 mg plus droperidol 2.5 rag,and group IV received dexamethasone plus normal saline as control. To observe nausea and vomiting,fever and scores of Words Descriptive Scale in the patients after laparoscopic operation. Results： Group I was helpful to decrease postoperative fever. Nausea and vomiting were reduced in group II （P〈0.05）. The fever rate, scores of Words Descriptive Scale and vomiting times obviously decreased in group III （P〈0.05）. Conclusion：Dexamethasone combined with droperidol is remarkably effective in preventing postop- erative nausea and vomiting and reducing the postoperative body temperature.