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小儿瑞芬太尼复合硝普钠控制性降压行全耳廓再造Ⅰ期手术的临床观察

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摘要 目的:探讨瑞芬太尼复合硝普钠控制性降压对先天性小耳畸形患儿全耳廓再造Ⅰ期手术的可行性和安全性。方法:择期行全耳廓再造Ⅰ期手术患儿30例,分为Ⅰ组(未降压组)和Ⅱ组(降压组)各15例。在静吸复合全身麻醉下,手术开始前静脉微泵输注瑞芬太尼0.15~0.25μg﹒kg-1﹒min-1,硝普钠1μg﹒kg-1﹒min-1开始,不超过3μg﹒kg-1﹒min-1,使平均动脉压降至55~65mmHg,并维持此水平至手术结束加压包扎过程中,逐渐减量停药。术中监测心电图(ECG)﹑心率(HR)﹑有创平均动脉压(MAP)﹑脉搏氧饱和度(SpO2),术前﹑降压30分钟﹑术毕分别做血气分析和血乳酸浓度(Lac),记录输液量﹑出血量﹑尿量﹑术后伤口引流量。结果:Ⅱ组降压后MAP与术前,术后及Ⅰ组相比差异有显著性(P<0.05),Ⅰ组﹑Ⅱ组HR变化差异无显著性,Ⅱ组ECG均为窦性心律,Ⅱ组术中失血量明显少于Ⅰ组,差异有显著性(P<0.05),术后引流管引流血量与未降压组差异无显著性。降压30分钟,停止降压后血乳酸浓度改变差异无显著性(P>0.05)。结论:瑞芬太尼复合硝普钠控制性降压可安全用于小儿全耳廓再造Ⅰ期手术,有效减少术中出血。
机构地区 昆明市儿童医院
出处 《现代医药卫生》 2010年第15期2308-2309,共2页 Journal of Modern Medicine & Health
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