原发性颅底软骨肉瘤CT和MRI诊断

CT and MRI diangnosis of primary chondrosarcoma at skull base

目的分析原发性颅底软骨肉瘤的CT和MRI表现,探讨CT和MRI在颅底软骨肉瘤中的诊断价值。方法搜集经病理组织学证实的9例颅底软骨肉瘤,全部病例均行CT和MRI平扫及增强。结果 9例CT平扫表现为等或略低密度的分叶状或类圆形软组织肿块,伴有不同程度的钙化,且形态不规则,呈散在沙粒样或弧形及粗糙团块状,同时合并骨质破坏;增强后病灶呈非均匀强化。MRI检查T1WI呈等低信号混杂影,T2WI呈高低信号混杂影,肿瘤内钙化在T1WI、T2WI均为无信号区,增强扫描明显不均匀性强化。结论颅底软骨肉瘤有较特有的CT和MRI影像学表现,是诊断颅底软骨肉瘤的有效方法 。

Objective To analyze CT and MRI features of primary chondrosarcoma at skull base,and to evaluate the value of CT and MRI in the diagnosis of this tumor. Methods Nine patients suffering from pathology-confirmed primary chondrosarcoma at skull base were enrolled in the study. Plain and enhanced CT and MRI were performed in all patients.Imaging findings were analyzed. Results Plain CT scan showed lobulate or cycloidal mass with calcification of different degrees accompanied with osseous destruction in all 9 patients. On enhanced CT,the tumors were inhomogeneously intensified.On MRI,the tumors were displayed as turbid masses with low or iso-signal on T1WI and inhomogeneous high-signal on T2WI with blank-signal calcified foci. Heterogeneous enhancement was observed in all cases on enhanced MRI. Changes in signal and density were in agreement with pathological results. Conclusion CT and MRI are useful for the diagnosis of primary chondrosarcoma at skull base due to their specific imaging features.