小儿哮喘与肺炎支原体感染的相关性

Relationship between asthma and mycoplasma pneumoniae infection in children

目的探讨小儿哮喘与肺炎支原体感染的临床相关性,提高小儿哮喘的治疗效果。方法收集住院治疗的120例支气管感染患儿与150例支气管感染伴哮喘患儿,通过血清学检查支原体感染情况,并汇总分析。将检查出的哮喘伴肺炎支原体感染患儿62例随机分为对照组与观察组,对照组给予抗生素、激素及支气管扩张剂治疗,观察组在此基础上加阿奇霉素序贯治疗,1个月后观察治疗效果,2个月后随访复发率。结果支气管感染组与支气管感染伴哮喘组在支原体感染方面比较,差异有统计学意义(P<0.01);对照组与观察组经治疗后,治愈率比较差异有统计学意义(P<0.05),治愈后复发率比较差异有统计学意义(P<0.01)。结论小儿发生哮喘时,应加强肺炎支原体的实验室检查,伴有肺炎支原体感染时,阿奇霉素序贯治疗能提高治愈率,有效控制复发率。

Objective To discuss the relationship between asthma and mycoplasma pneumoniae infection in children,improve the therapeutic effect of asthma in children.Methods Collect 120 children of bronchus infections and 150 children of bronchus infections with asthma,check mycoplasma by serology.Evenly 62 children with asthma and mycoplasma pneumoniae infection.The control group was given antibiotics,hormones and bronchodilator therapy,the observation group plused azithromycin sequential therapy,after one month observe the therapeutic effect,after two months observe relapse.Results Bronchial infection and bronchial asthma associated with infection in comparison of MP infection,has a very significant statistical difference（P〈0.01）;the cure rate had a significant statistical difference between the tow groups after treatment（P〈0.05）,and relapse rate with a significant statistical difference（P〈0.01）.Conclusion We should strengthen the inspection of mycoplasma pneumoniae when children with asthma.When it complicated with mycoplasma pneumoniae infection,azithromycin sequential therapy can improve the cure rate and effectively control the relapse rate.