地塞米松生产中毒性物质泄漏的定性定量分析

Qualitative and Quantitative Analyses on Leakage of Toxic Materials in Dexamethasone Production

采用预先危险性分析和事故树分析剖析地塞米松生产过程中毒性物质产生中毒事故的危险性,指出溴甲烷和氟化氢是典型毒物。同时,利用泄漏和扩散模型定量分析它们泄漏所造成的危险性,结果表明:溴甲烷泄漏时,地面轴线浓度可以达到92.3mg/m^3,远大于其急性中毒阈值19mg/m^3(经皮),并制定了相应的预防性工程措施。

Preliminary hazardous analysis and fault tree analysis were applied to assay the hazard of toxication accidents caused by toxic materials in the course of dexamethasone production, it pointed out that bromomethane and HF were typical toxic materials. And leakage and diffusion models were used to quantitative analysis on the hazard caused by leakage.