超声对甲状腺结节内粗大钙化灶与甲状腺癌关系的评价

Assessment of association between macrocalcification in thyroid nodule and thyroid carcinoma with ultrasound

目的分析甲状腺结节内不同类型粗大钙化与甲状腺癌的关系。方法回顾性分析2009年2—10月行甲状腺超声检查发现结节同时伴粗大钙化之后进行甲状腺结节切除手术的患者169例，将结节内粗大钙化按超声表现分成三型，比较每一型粗大钙化与甲状腺癌发生的相关性。结果176个伴有粗大钙化的甲状腺结节中122个为恶性，54个为良性。在粗大钙化分型中，不规则形钙化常见于恶性甲状腺结节，恶性比例为82．9％（34／41），孤立团片状钙化出现在甲状腺恶性结节中相对减少，恶性比例为58．5％（31／53），弧形钙化介于两者之间，恶性比例为69．5％（57／82）。结论超声对评价伴有粗大钙化的甲状腺结节的良恶性具有重要意义。

Objective To determine the association between macrocalcificatoin in thyroid nodule and thyroid carcinoma. Methods Sonogram of 169 patients of thyroid nodule with macrocalcification was retrospectively analyzed. The uhrasonographic finding was compared with pathological results after excision. Macrocalcification was divided into three types and assessed the relation between each type macrocalcification and thyroid carcinoma. Results Macrocalcification was detected in 176 nodules, 122 were malignant, and 54 were benign. Irregular macrocalcification were more common in malignant nodule （82.9% ,34/41 ）, the malignant risk of solitary macrocalcification were lower （58.5%, 31/53 ）, and the malignant risk of curvilinear macrocalcification were between irregular macrocalcification and solitary macrocalcification （69.5%, 57/82）. Conclusion Uhrasonography can play an important role in differentiating benign and malignant thyroid nodule macrocalcification.