奥曲肽治疗23例粘连性肠梗阻疗效观察

Observation on Efficiency of 23 Cases of Abhesive Yntestinal Obstruction

目的探讨奥曲肽治疗粘连性肠梗阻的疗效。方法 41例肠梗阻患者随机分为奥曲肽组(23例)和对照组(18例),奥曲肽组采用奥曲肽0.1mg皮下注射,每8小时一次,连用3～7d,并联合对照组的常规治疗,对照组只给予常规治疗。结果两组疗效差异有显著性。奥曲肽组临床症状明显缓解,肛门排气时间明显提前,住院时间明显缩短,胃肠减压量明显减少(P<0.05)。奥曲肽组治愈率明显高于对照组。结论奥曲肽治疗粘连性肠梗阻具有显著且安全的疗效。

Objective To investigate the effect of octreotide in abhesive intestinal obstruction. Methods 41 cases of abhesive intestinal obstruction selected in our hospital were divided into two groups：octreotide group （23 cases） and control group（18 cases）. The patients in the octreotide group were treated with routine therapy and hypodermic injection octreotide （0.1mg/8h）,successive inject 3 -7days,the patients in the control group were only treated with routine therapy. Results There are very significantly difference between two group.The remission rate of symptoms for Octreotide group were obtained obviously,the average annual exhaust time was significantly earlier than that in control group,and the average hospitalization time of octreotide group were shorter than that of control, gastrointestinal decompression rate of octreotide group were significant declines than control group（P〈0.05）.The cure rate of octreotide group were apperenfly higher than control group. Conclusion Octreotide is efficient safe in the treatment of abhesive intestinal obstruction.