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RASSF1A基因甲基化与妇科肿瘤发生发展的关系研究进展 被引量：1

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作者 董延磊 张师前
机构地区 山东大学齐鲁医院
出处 《山东医药》 CAS 北大核心 2010年第26期111-112,共2页 Shandong Medical Journal
基金 山东省高等学校科技计划基金资助项目(J08LG20)
关键词 抑癌基因 Ras相关区域家族1基因 子宫颈癌 卵巢癌 子宫内膜癌
分类号 R737.3 [医药卫生—肿瘤]
  • 相关文献

参考文献18

  • 1Tommasi S,Dammann R,Jin SG,et al.RASSF3 and NORE1:identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1[J].Oncogene,2002,21(17):2713-2720.
  • 2Shivakumar L,Minna J,Sakamaki T,et al.The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation[J].Mol Cell Biol,2002,22(12):4309-4318.
  • 3Nephew KP,Huang TH.Epigenetic gene silencing in cancer initiation and progression[J].Cancer Lett,2003,190(2):125-133.
  • 4Li Y,Wei Q,Cao F,et al.Expression and promoter methylation of the RASSF1A gene in sporadic breast cancers in Chinese women[J].Oncol Rep,2008,19(5):1149-1153.
  • 5Pfeifer GP,Yoon JH,Liu L,et al.Methylation of the RASSF1A gene in human cancers[J].Biol Chem,2002,383(6):907-914.
  • 6Yu MY,Tong JH,Chan PK,et al.Hypermethylation of the tumor suppressor gene RASSF1A and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers[J].Int J Cancer,2003,105(2):204-209.
  • 7Cohen Y,Singer G,Lavie O,et al.The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix[J].Clin Cancer Res,2003,9(8):2981-2984.
  • 8Lai HC,Lin YW,Chang CC,et al.Hypermethylation of two consecutive tumor suppressor genes,BLU and RASSF1A,located at 3p21.3 in cervical neoplasias[J].Gynecol Oncol,2007,104(3):629-635.
  • 9Kuzmin I,Liu L,Dammann R,et al.Inactivation of RAS association domain family 1A gene in cervical carcinomas and the role of human papillomavirus infection[J].Cancer Res,2003,63(8):1888-1893.
  • 10Makarla PB,Saboorian MH,Ashfaq R,et al.Promoter hypermethylation profile of ovarian epithelial neoplasms[J].Clin Cancer Res,2005,11(15):5365-5369.

同被引文献17

  • 1南芳芳,姜洁,夏敏,董,冯进波.RASSF1 A基因在子宫内膜癌组织中的表达及意义[J].山东大学学报（医学版）,2007,45(1):94-96. 被引量：5
  • 2Schuurman MS, van Den Einden LC, Massuger LF, et al. Trends in incidence and survival of Dutch women with vulvar squamous cell carcinoma[J]. Eur J Cancer, 2013, 49(18): 3872-3880.
  • 3Hockel M, Schmidt K, Bommann K, et al. Vulvar field resection: novel approach to the surgical treatment of vulvar cancer based on ontogenetic anatomy[J]. Gynecol Oncol, 2010, 119(1): 106-113.
  • 4Richter AM, Pfeifer GP, Dammann RH. The RASSF proteins in cancer; from epigenetic silencing to functional characterization[J]. Biochim Biophys Acta, 2009, 1796(2): 114-128.
  • 5Mitra S, Mazumder Indra D, Basu PS, et al. Alterations of RASSF1A in premalignant cervical lesions: clinical and prognostic significance[J]. Mol Carcinog, 2012, 51(9): 723-733.
  • 6Maliukova AV, Loginov VI, Khodyrev DS, et al. Methylation of the putative tumor suppressor gene, RASSFIA, in primary cervical tumors[J]. Mol Biol (Mosk), 2004, 38(6): 1005-1013.
  • 7Fiolka R, Zubor P, Janusicova V, et al. Promoter hypermethylation of the tumor-suppressor genes RASSFIA, GSTP1 and CDH1 in endometrial cancer[J]. Oncol Rep, 2013, 30(6): 2878-2886.
  • 8Shi H, Li Y, Wang X, et al. Association between RASSF1A promoter methylation and ovarian cancer: a meta-analysis[J]. PLoS One, 2013, 8(10): e76787.
  • 9Zhang Q, Hu G, Yang Q, et al. A multiplex methylation-specific PCR assay for the detection of early-stage ovarian cancer using cell-free serum DNA[J]. Gynecol Oncol, 2013, 130(1): 132-139.
  • 10Dammann R, Li C, Yoon JH, et al. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressol locus 3p21.3 [J]. Nat Genet, 2000, 25(3): 315-319.

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山东医药
2010年 第26期

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