80例三聚氰胺致婴幼儿泌尿系结石治疗的临床分析

A retrospective clinical study of 80 infants with urolithiasis caused by the consumption of melamine-contaminated milk powder formula

目的回顾性分析80例三聚氰胺致婴幼儿泌尿系结石患儿的临床资料,提高对婴幼儿泌尿系结石的治疗水平。方法纳入2008年9月～2008年11月在兰州大学第二医院诊治的80例三聚氰胺致婴幼儿泌尿系结石患儿,采用内科保守治疗或外科干预(输尿管镜下碎石及输尿管支架管置入术、微创经皮肾镜碎石术MPCNL)。结果 37例患儿采用内科保守治疗两周后30例结石完全排除,7例结石减小;43例采用外科干预,术后24h内患儿均出现多尿,尿量约为800～2500mL。复查B超,41例结石完全排出,2例结石减小。结论内科保守治疗和外科干预治疗对三聚氰胺致婴幼儿泌尿系结石患儿具有明显疗效,其中微创外科治疗可作为三聚氰胺致婴幼儿泌尿系结石梗阻患儿的首选方法。

Objective To improve the with urolithias caused by consumption of the treatment of infant urolithias by reviewing the clinical information of 80 infants melamine-contaminated milk powder. Methods 80 cases diagnosed as urolithias from Sept. 2008 to Nov. 2008 in the Second Hospital of Lanzhou University were included in the study.All cases were treated with traditional and surgical intervention. The surgical intervention included： ① crushing the stone under ureter tube and supporting the ureter with tube; ②mininmally invasive percautaneous nephrolithotomy（MPCNL）. Results Among the 37 infants who underwent two- week traditional intervention, 30 discharged the stone completely and 7 had the size of stone reduced obviously. 43 infants accepted surgical intervention. They all had polyuria after 24 hours and the amount of urine was about 800 to 2 500 mL. 41 of them cases discharged the stone completely. Conclusion Both traditional and surgical intervention were effective to cure infants fed with melamine-containted milk powder, but the minimally invasive surgical intervention was considered the primary treatment.