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大肠癌表皮生长因子受体与增殖细胞核抗原检测的意义 被引量:1

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摘要 目的:探讨大肠癌表皮生长因子受体(EGFR)和增殖细胞核抗原(PCNA)表达的临床意义。方法:采用免疫组化法,对72例大肠癌石蜡组织表皮生长因于和增殖细胞核抗原进行研究,并以40例正常大肠粘膜组织为对照组。结果:大肠癌组织EGFR表达阳性率和PCNA计数值,均明显高于对照组(P<0.01),大肠癌组中伴淋巴结转移者和复发者EGFR表达阳性率和PCNA计数值,均分别高于不伴淋巴结转移者和无复发者(P<0.01)。结论:EGFR和PCNA联合检测,可作为判断大肠癌转移情况及预后的重要指标。
出处 《临床荟萃》 CAS 1999年第4期148-149,共2页 Clinical Focus
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