磷酸多肽对牙齿再矿化的实验研究

Teeth remineralization test study for phosphopeptide

目的探索安全、有效、简便的生物制品防治龋病的新途径。方法根据牙齿再矿化理论，进行了实验，说明磷酸多肽（Phosphopcptide，TD201）防治龋病的作用机制、效果及临床应用前景。结果实验证明，磷酸多肽能携带钙、磷成份并与羟磷灰石（HA）有较强亲合力，使牙齿再矿化过程加强。结论磷酸多肽能安全有效地预防和治疗龋病，并可广泛地应用于临床。

Objective To explore a new method for effective and safe prevention and treatment of caries. MethodsAccording to the theory of remineralization of teeth, the mechanism and possibility of clinical application of toothremineralization with phmphOPeptide were investigated. Results Phosphopeptide, with Ca and P, had an ability of affinitywith hydroxyapatite and enhancing remineralization of teeth. Conclusion Phosphopeptide can prevent and treat toothdecay effectively and can be applied in clinic safely.