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以自身免疫性溶血性贫血起病的华氏巨球蛋白血症1例并文献复习 被引量：3

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摘要 目的:提高对华氏巨球蛋白血症(WM)的认识水平。方法:报告1例WM患者的临床表现及实验室检查,并进行相关文献复习,为诊断和治疗提供思路。结果:患者骨髓涂片示浆细胞样淋巴细胞占12.50%,血清单克隆IgM最高达91.50g/L、直接抗人球蛋白试验阳性、无骨质破坏。结论:该例明确诊断为WM。骨髓涂片见浆细胞样淋巴细胞、血清中单克隆IgM>10g/L、无骨质破坏并结合临床表现可诊断WM。
作者 黄继贤 肖捷 肖健
机构地区 汕头大学医学院附属粤北人民医院血液内科 汕头大学医学院附属粤北人民医院急诊科 汕头大学医学院附属粤北人民医院药剂科
出处 《临床血液学杂志》 CAS 2010年第4期421-423,共3页 Journal of Clinical Hematology
关键词 贫血 溶血性 自身免疫性 华氏巨球蛋白血症
分类号 R556.6 [医药卫生—血液循环系统疾病]
  • 相关文献

参考文献16

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同被引文献42

  • 1任昊.肾性贫血[J].实用医学杂志,2007,23(5):768-769. 被引量：8
  • 2Birgeggtrd G. Managing anemia in lymphoma and multiple myeloma. Ther Clin Risk Manag,2008,4:527-539.
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  • 5Silvestris F, Cafforio P, Tucci M, et al. Negative regulation of eirthroblast maturation by Fas-L ( + )/TRAIL ( + ) highly malignant plasma cells : a major pathogenetic mechanism of anemia in muhiple myeloma. Blood,2002, 99 : 1305-1313.
  • 6Silvestris F, Tucci M, Cafforio P, et al. Fas-L up-regulation by highly malignant myeloma plasma cells : role in the pathogenesis of anemia and disease progression. Blood, 2001,97:1155-1164.
  • 7Cucuianu A, Patiu M, Rusu A, et al. Hepcidin and multiple myeloma related anemia. Med Hypotheses ,2006,66:352-354.
  • 8Balogh A, Bosze S, Horvgtti K, et al. Role of iron metabolism- regulator hepcidin in perinatal iron homeostasis. Or,: Hefil,2010, 151:83-91.
  • 9De Domenico I, Ward DM, Kaplan J, et al. Hepeidin and ferroportin: the new players in iron metabolism. Semin Liver Dis, 2011,31 : 272-279.
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临床血液学杂志
2010年 第4期

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