我院711例非淋菌性尿道炎患者泌尿生殖道支原体感染及耐药情况分析

Analysis of Uregenital Tract Mycoplasma Infection of 711 Patients in Our Hospital and Drug Resistance

目的:了解我院非淋菌性尿道炎(NGU)患者支原体感染及耐药情况,为临床合理应用抗生素提供参考。方法:采用支原体诊断试剂盒对拟诊为NGU的患者进行支原体培养、鉴定和药物敏感试验。结果:711例疑似NGU患者中支原体培养为阳性的360例,阳性率为50.66%,其中对解脲支原体(Uu)单独感染的235例,阳性率为33.05%;人型支原体(Mh)单独感染的30例,阳性率为4.22%;Uu+Mh感染的95例,阳性率为13.36%。药物敏感试验结果显示,Uu单一感染首选药物为交沙霉素、强力霉素、美满霉素、克拉霉素及四环素,对Uu+Mh混合感染首选药物为强力霉素、交沙霉素、美满霉素。结论:Uu是引起泌尿生殖道感染的主要病原菌,对支原体感染的临床用药应根据支原体的种类和药物敏感试验结果进行选择。

OBJECTIVE：To investigate mycoplasma infection and drug susceptibility in patients with non-gonococcus urethritis （NGU）,and to provide reference for rational use of antibotics in patients with mycoplasma infection.METHODS：Mycoplasma diagnosis reagent box was used to culture and identify mycoplasma from suspected patients with NGU,and to conduct drug sensitivity test.RESULTS：360 cases of positive mycoplasma among 711 suspected NGU patients （positive rate was 50.66%）,Uu positive were 235 cases （positive rate 33.05%）;Mh positive were 30 cases （positive rate 4.22%）;Uu＋Mh positive were 95 cases （positive rate 13.36%）.Results of drug sensitivity test showed josamycin,doxycycline,minocycline,clarithromycin and tetracycline were best choice for Uu single infection,and josamycin,doxycycline,minocycline for Uu＋Mh infection.CONCLUSION：Uregenital tract infections are mainly caused by Uu.Clinical medication for mycoplasma infection should be in accordance with the type of mycoplasma and results of drug sensitivity test.