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中毒性表皮坏死松解症发病机制研究进展 被引量:9

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摘要 中毒性表皮坏死松解(toxic epidermal necrolysis,TEN)为一种临床常见的重症药疹,其病情危重,病死率高。目前TEN发病机制的研究仍主要集中在免疫系统,研究表明TEN主要是通过Fas/FasL、穿孔/颗粒酶途径致使角质形成细胞凋亡的过程,在此过程中多种细胞因子参与其间。本文旨在从TEN的发病机制进行综述。
作者 张飞 张学军
出处 《中国麻风皮肤病杂志》 2010年第7期499-501,共3页 China Journal of Leprosy and Skin Diseases
关键词 TEN 发病机制
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参考文献19

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同被引文献76

  • 1焦德清,刘金芳,王晓刚.大剂量丙种球蛋白加激素治疗重症渗出性红斑的疗效分析[J].川北医学院学报,2004,19(4):64-64. 被引量:2
  • 2陈金波,王宝玺.中毒性表皮坏死松解型药疹/重症多形红斑的发病机制[J].国际皮肤性病学杂志,2007,33(5):320-322. 被引量:17
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