四川省壤塘县大骨节病区儿童硒营养状况分析

Study on the selenium nutrition of children in Kaschin-Beck disease endemic areas in Rangtang county,Sichuan province

目的分析国内大骨节病病区儿童发硒含量及其影响因素,为制定合适的大骨节病防控措施提供依据。方法使用氢化物产生原子荧光光谱法(HG-AFS)测定儿童头发、大米和糌粑的含硒量,分析不同年龄、不同性别儿童的头发含硒特征及膳食结构对儿童硒营养状况的影响。利用SPSS14.0软件进行统计分析,P<0.05为差异有统计学意义。结果学龄前期(1～6岁)和学龄期(7～15岁)儿童头发的平均含硒量分别为(95.9±25.3)μg.kg-1(n=19)和(117.4±40.6)μg.kg-1(n=48),前者的发硒含量明显低于后者(t=-2.139,P=0.036)。对于学龄前期儿童,男童头发的含硒量略高于女童(t=0.253,P=0.803)。对于学龄期儿童,男童的发硒含量明显高于女童(t=2.560,P=0.014)。学校食堂的大米含硒量约为当地农户自制糌粑含硒量的2.5倍。结论膳食结构与儿童的硒营养状况直接相关,同时,适当的体育锻炼对改善大骨节病区儿童的硒营养状况也有一定的积极作用。

Objective To investigate the selenium concentration of child hairs and its influencing factors in Kaschin-Beck disease endemic regions in China.Methods The selenium concentration was determined for children hair,rice and tsamba samples by hydride generated atomic fluorescence spectrometry（HG-AFS）.The information of age,gender and food structure of selenium nutrient status for children was collected and analyzed using the statistical software of SPSS 14.0.Results The average hair selenium concentration was（95.9±25.3）μg·kg^-1 （n=19）and（117.4±40.6）μg·kg^-1（n=48） for preschool and school children respectively.The concentration of selenium in hair of preschool children was significantly lower than that of school children（t=-2.139,P=0.036）.The average hair selenium concentration in boys was significantly higher than that in girls for the school children （t=2.560,P=0.014）.The selenium concentration of rice in school cafeteria was as 2.5 times as that of tsamba made by local farmers.Conclusion The selenium nutrient status in children is directly associated with food structure.It is important to provide children with rich selenium nutrient food and advocate for physical exercises.