血清尿酸与脑梗死危险因素的相关性分析

Relationship between Serum Uric Acid Level and Risk Factors for Cerebrovascular Disease in Patients with Cerebral Infarction

目的分析脑梗死男性患者血清尿酸水平与脑血管病危险因素的相关性。方法选择脑梗死住院患者678例,根据临床危险因素、实验室检查指标,进行统计分析。结果脑梗死患者中,伴高血压病、冠心病、糖尿病、有高甘油三酯、高血糖、低高密度脂蛋白胆固醇血症者血清尿酸水平较高(P<0.05)。Logistic回归分析结果显示,脑梗死患者中,高血压病、高甘油三酯、高血糖及低高密度脂蛋白胆固醇血症与高尿酸血症密切相关。结论高尿酸血症不仅与高血压病、高甘油三酯、高血糖及低高密度脂蛋白胆固醇血症关系密切,而且影响脑梗死患者的发生和预后。

Objective To analyze the relationship between serum uric acid level and risk factors for cerebrovascular disease in male patients with cerebral infarction（CI）.Methods 678 patients with CI,who admitted in the neurological department of Zengcheng People＇s hospital were recruited.The clinical,laboratory data were recorded.The relationship between serum uric acid level and risk factors for cerebrovascular disease was analyzed.Results Increased uric acid values was found in men,hypertension,coronary heart disease,diabetes and patients with hypertriglyceridemia,low high-density lipoprotein cholesterolemia and hyperglycemia（P0.05）.Logistic regression analysis showed that higher uric acid was closely related to hypertension,and patients with hypertriglyceridemia,low high-density lipoprotein cholesterolemia and hyperglycemia.Conclusion Hyperuricemia was closely related with hypertension,high triglycerides,high blood glucose and low high-density lipoprotein cholesterol,and affected the incidence and prognosis of patients with CI.