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普罗布考治疗对急性冠脉综合征患者炎症反应的临床观察 被引量:1

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摘要 目的观察口服普罗布考对急性冠脉综合征患者血清炎性指标及血脂水平的影响,探讨普罗布考的抗炎、调脂作用。方法选择2008年10月至2009年10月在我院住院患者中确诊为急性冠脉综合征的患者,随机分为常规治疗组(扩冠、抗栓、ACEI、β受体阻滞剂、他汀)和普罗布考组(常规治疗+普罗布考)两组。分别测定入院时、入院一周后的血脂水平和血清炎性标志物:CRP、IL-6的值,对比观察普罗布考对炎症反应的影响。结果应用普罗布考治疗一周后炎性标志物水平显著低于常规治疗组,TC、LDL-C的水平显著低于常规治疗组(P<0.05)。单纯应用他汀类药物治疗一周后炎性标志物水平降低不明显(P>0.05)。结论普罗布考具有较强的抗炎作用,在急性冠脉综合征治疗中可以与他汀类药物联合应用以加强抗炎、降脂的效果。
作者 赵军 周斐昊
出处 《中国实用医药》 2010年第21期137-138,共2页 China Practical Medicine
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