36例卵巢Krukenberg瘤的临床病理特点分析

Analyzing Clinical and Pathological Features of 36 Cases Krukenberg Tumor

目的探讨卵巢Krukenberg瘤的临床病理特点,提高对本病的重视。方法回顾性分析经手术病理证实的36例卵巢Krukenberg瘤患者的临床病理资料。结果卵巢krukenberg瘤多见于绝经前女性(23/36),多见于双侧卵巢(22/36);原发灶病理类型多为低分化腺癌及黏液腺癌;胃来源的21例,结直肠来源13例,阑尾来源2例,多数患者1年内死亡。结论了解卵巢Krukenberg瘤的临床病理特点,有助于提高诊断率;诊断卵巢恶性肿瘤时应行胃肠道检查排除转移癌;诊断胃肠道恶性肿瘤时,应行盆腔检查排除转移至卵巢;卵巢Krukenberg瘤的首选治疗方法为根治性手术加化疗。

Objective Investigating the clinical and pathological feature of Krukenberg tumor to pay more attention to this disease. Methods Clinical and histological data of 36 cases with Krukenberg tumor were analyzed retrospectively. Results Krukenberg tumor occurs more often in women before menopause （23/36） and mostly bilateral （22/36）.Most common pathological types of the primary carcinomas are poorly differentiated adenocarcinoma or myxedema.21 cases come from gastric carcinoma,13 cases from intestine carcinoma,2 cases from appendiceal mucous carcinoid. Prognosis of Krukenberg turmor is poor,most patients died in l year. Conclusion Knowing the clinical feature of Kmkenberg tumor lead to right diagnosis.Metastasized ovarian tumor should always be excluded when an ovarian malignant neoplasm is observed.Patients with metastatic ovarian neoplasm should be examined for primary gastrointestine neoplasm. Operation together with chemotherapy is the first choice to Kmkenberg tumor patients.