冠心病合并2型糖尿病危险因素及冠脉病变特点分析

The Risk Factors and Characteristics of Coronary Artery Lesion in Patients with Coronary Heart Disease Complicated with Diabetes Mellitus Ⅱ

目的探讨冠心病(coronary heart disease,CHD)合并2型糖尿病(DM)危险因素及冠状动脉病变特点。方法回顾性分析经冠脉造影确诊的596例CHD患者临床资料,其中合并DM组130例,非DM组466例,比较两组冠脉病变影像资料与危险因素。结果合并DM的CHD患者高血压、高甘油三酯(TG)、低高密度脂蛋白胆固醇(HDL-C)、高血尿酸(UA)发生比例较不合并DM的单纯CHD患者高;冠状动脉造影显示冠状动脉多支病变发生率高,病变程度重,较非DM组差异有统计学意义(P<0.05)。结论 CHD合并DM患者合并危险因素多,冠脉病变较重。

Objective To investigate the risk factors and characteristics of coronary artery lesion in patients with coronary heart disease with diabetes mellitus II. Methods 596 patients with coronary heart disease （CHD） included them with diabetes mellitus（ DM group, n = 130） and them without diabetes mellitus （No - DM group, n = 466）. The data of coronary arteriography and the related risk factors including FPG, TC, TG, smoking, HDL- C, LDL- C and UA were compared between two groups. Results TG and HDL- C were significantly higher in CHD with DM group than those in CHD without DM group（P 〈0.05 ）. The data of coronary arteriography showed more severe and more - vessel lesions in the CHD with DM group than those in CHD without DM group（P 〈0.05）. Conclusion The severity of coronary artery lesion related with the amount of risk factors in CHD with DM.