LMNA基因与家族性扩张型心肌病

Familial dilated cardiomyopathy and lamin A/C gene

扩张型心肌病是儿童心肌病的常见类型,有明显的遗传倾向,具有家族聚集性.已发现有20多种基因突变与家族性扩张型心肌病有关,其中lamin A/C基因是最常见的致病基因之一.

Dilated cardiomyopathy（DCM） is one common type of children＇s cardiomyopathy,and it has a significant genetic and familial predisposition.There are more than twenty kinds of gene mutation having relation with familial DCM.LaminA/C is one of the mutant genes that is associated with familial DCM,which have more higher rate of sudden death.